Modifiable risk factors and symptom progression in dementia over up to 8 years-Results of the DelpHi-MV trial.

ABSTRACT:

Introduction

This study investigated the association between modifiable factors and symptom progression in dementia over up to 8 years.

Methods

Multilevel growth curve models assessed the role of modifiable risk factors (low education, hearing impairment and its treatment, depression, physical inactivity, diabetes and its treatment, smoking, hypertension and its treatment, obesity, alcohol consumption, social isolation, and visual impairment) on cognitive and functional trajectories in 353 people with dementia.

Results

Higher education was associated with higher initial cognitive status but faster decline. Antidiabetic medication was associated with slower cognitive decline, whereas depression and visual impairment were linked to low baseline functioning and faster co

SUBMITTER: Blotenberg I 

PROVIDER: S-EPMC11730075 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature