Ontology highlight
ABSTRACT:
SUBMITTER: Pickering J
PROVIDER: S-EPMC117302 | biostudies-literature | 2002 Jun
REPOSITORIES: biostudies-literature
Nucleic acids research 20020601 12
Association studies using common sequence variants or single nucleotide polymorphisms (SNPs) may provide a powerful approach to dissect the genetic inheritance of common complex traits. Such studies necessitate the development of cost-effective, high throughput technologies for scoring SNPs. The method described in this paper for the co-detection of both alleles of a SNP in a single homogeneous reaction combines the specificity of a high fidelity DNA ligation step with the power of rolling circl ...[more]