Comparison of ex vivo lesion formation for two adjacent radiofrequency applications with very high-power short-duration in various inter-lesion times.

ABSTRACT:

Background/objectives

Very high-power and short-duration (vHPSD) ablation with QDOT MICRO™ facilitates speedy and safe ablation for pulmonary vein isolation. A brief time interval between ablating two neighboring sites with vHPSD may potentially influence the size and geometry of the lesions. This study evaluates lesion formation when delivering adjacent applications using vHPSD at various inter-lesion times (ILTs).

Methods

Radiofrequency applications were conducted by QDOT MICRO™ catheter with 90 W of strength and 4 s duration. Fresh swine heart tissue on the epicardium was ablated with 10 g of the contact force. Lesions were created using a single application (SA) and double applications (DA) of adjacent lesions with a 6 mm distance between them as measured on the 3D mappi

SUBMITTER: Hanaki Y 

PROVIDER: S-EPMC11730985 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature