Characterisation of a Betasatellite Associated With Tomato Yellow Leaf Curl Guangdong Virus and Discovery of an Unusual Modulation of Virus Infection Associated With C4 Protein.

ABSTRACT: Tomato yellow leaf curl Guangdong virus (TYLCGdV), a monopartite begomovirus first identified in 2004, remains poorly characterised. In this study, we demonstrate that TYLCGdV associates with a betasatellite, TYLCGdB, and the βC1 protein encoded by TYLCGdB is essential for symptom development. We also explore the role of TYLCGdV C4 protein by generating a C4-deficient infectious clone (TYLCGdV_mC4), revealing a dynamic role for TYLCGdV C4. Specifically, viral accumulation in TYLCGdV_mC4/TYLCGdB-inoculated plants was significantly lower than that in TYLCGdV/TYLCGdB-inoculated plants at 7 and 14 days post-inoculation (dpi), but surpassed that of TYLCGdV/TYLCGdB-inoculated plants by 25 dpi. Furthermore, although C4 proteins in other begomoviruses typically exhibit one or m

SUBMITTER: Li Z 

PROVIDER: S-EPMC11732742 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature