Cone Beam Online Adaptive Radiation Therapy: A Promising Approach for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma?

ABSTRACT:

Purpose

Daily online adaptive radiation therapy (oART) opens the opportunity to treat gastric mucosa-associated lymphoid tissue (MALT) lymphoma with a reduced margin. This study reports our early experience of cone beam computed tomography (CBCT)-based daily oART treating gastric MALT lymphoma with breath-hold and reduced margins.

Methods and materials

Ten patients were treated on a CBCT-based oART system. Organs at risk (OARs) and the clinical target volume (CTV) were adjusted based on the daily CBCT. Planning target volume (PTV) was derived from the CTV with a 0.5 to 0.7 cm margin with breath-hold. Multiple beam arrangements were compared during the preplanning phase to ensure minimal monitor unit (MU) for patient comfort and breath-hold reproducibility. For 108 fractions

SUBMITTER: Zhong X 

PROVIDER: S-EPMC11733034 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature