Health Care Resource Utilization With Dronedarone Versus Sotalol Following Catheter Ablation in Adults With Atrial Fibrillation.

ABSTRACT:

Background

Clinical trials support dronedarone use for atrial fibrillation (AF) following catheter ablation (CA); however, comparative data on health care resource utilization (HCRU) with other antiarrhythmic drugs are lacking.

Methods

Retrospective analysis of Merative MarketScan databases (January 01, 2012-March 31, 2020) comparatively assessed HCRU in US adults with AF who received dronedarone or sotalol post-CA. Patients with ≥ 12-months' pre-CA data were followed from post-CA index treatment to disenrollment, death, or study end. Sotalol-treated patients were propensity score-matched (1:1) with dronedarone-treated patients. Events/100 patient-years (PY) were analyzed by univariate generalized-linear model with Poisson distribution. Cumulative incidence was analyzed over

SUBMITTER: Zeitler EP 

PROVIDER: S-EPMC11733741 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature