Nasal microbiota predictors for methicillin resistant Staphylococcus colonization in critically ill children.

ABSTRACT:

Background

Surveillance cultures to identify patients colonized with methicillin-resistant Staphylococcus aureus (MRSA) is recommended at pediatric intensive care unit (PICU) admission but doesn't capture other methicillin-resistant Staphylococcus and is resource intensive. We determined the prevalence and identified nasal microbiome predictors for methicillin-resistant Staphylococcus colonization at the time of PICU admission.

Study design

A prospective cohort study was performed in a 20-bed pediatric intensive care unit (PICU) between 2020-2021. Anterior nares nasal swabs processed for MRSA culture, nasal microbiome and mecA+ qPCR were obtained within first five days after PICU admission. Predictive values of methicillin-resistant Staphylococcus carriage on symptoms of inf

SUBMITTER: Zani K 

PROVIDER: S-EPMC11734933 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature