Impact of Metabolic Health and Its Changes on Erosive Esophagitis Remission: A Cohort Study.

ABSTRACT:

Background/aims

We aim to compare the remission of erosive esophagitis (EE) among individuals with different phenotypes based on their metabolic health and obesity status and investigate the impact of changes in metabolic health on the EE remission.

Methods

Asymptomatic adults (n = 16 845) with EE at baseline, who underwent follow-up esophagogastroduodenoscopy (EGD) were categorized into 4 groups as follows: metabolically healthy (MH) nonobese, metabolically unhealthy (MU) nonobese, MH obese, and MU obese. EE was defined as grade A or higher mucosal breaks observed using esophagogastroduodenoscopy.

Results

During a median follow-up of 2.2 years, the remission rates of EE were 286.4/10³, 260.1/10³, 201.5/10³, and 219.9/10³ pe

SUBMITTER: Kim NH 

PROVIDER: S-EPMC11735195 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature