Impact of type of mechanical circulatory support before transplant on postorthotopic heart transplantation infections.

ABSTRACT:

Background

Infections after orthotopic heart transplantation (OHT) cause significant morbidity and mortality. Concurrent with increased pre-OHT temporary mechanical circulatory support (MCS), there have been recent concerns of a perceived increase in infections post-OHT. We examined the association between pre-OHT temporary versus durable MCS and post-OHT infection.

Methods

We performed a single-center retrospective review of patients who received OHT at Tufts Medical Center between January 2014 and April 2022. Our composite outcome was the occurrence of bacteremia, invasive fungal infections, opportunistic infections, or skin/soft tissue infections of device sites within 1-year post-OHT. We used Cox proportional hazards models to assess the relationship between the type of

SUBMITTER: Trottier CA 

PROVIDER: S-EPMC11735309 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature