Air Pollution and Breast Cancer Incidence in the Multiethnic Cohort Study.

ABSTRACT:

Purpose

Recent studies suggested fine particulate matter (PM_2.5) exposure increases the risk of breast cancer, but evidence among racially and ethnically diverse populations remains sparse.

Materials and methods

Among 58,358 California female participants of the Multiethnic Cohort (MEC) Study followed for an average of 19.3 years (1993-2018), we used Cox proportional hazards regression to examine associations of time-varying PM with invasive breast cancer risk (n = 3,524 cases; 70% African American and Latino females), adjusting for sociodemographics and lifestyle factors. Subgroup analyses were conducted for race and ethnicity, hormone receptor status, and breast cancer risk factors.

Results

Satellite-based PM_2.5 was associated with a statistica

SUBMITTER: Wu AH 

PROVIDER: S-EPMC11735325 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature