Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis.

ABSTRACT: In organisms ranging from vertebrates to plants, major components of centromeres are rapidly evolving repeat sequences, such as tandem repeats (TRs) and transposable elements (TEs), which harbour centromere-specific histone H3 (CENH3)^1,2. Complete centromere structures recently determined in human and Arabidopsis suggest frequent integration and purging of retrotransposons within the TR regions of centromeres^3-5. Despite the high impact of 'centrophilic' retrotransposons on the paradox of rapid centromere evolution, the mechanisms involved in centromere targeting remain poorly understood in any organism. Here we show that both Ty3 and Ty1 long terminal repeat retrotransposons rapidly turnover within the centromeric TRs of Arabidopsis species. We demonstrate that the T

SUBMITTER: Tsukahara S 

PROVIDER: S-EPMC11735389 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature