Comparison of Arterial Spin-Labeling and DSC Perfusion MR Imaging in Pediatric Brain Tumors: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Brain tumors are a leading cause of mortality in children. Accurate tumor grading is essential to plan treatment and for prognostication. Perfusion imaging has been shown to correlate well with tumor grade in adults, however there are fewer studies in pediatric patients. Moreover, there is no consensus regarding which MR perfusion technique demonstrates the highest accuracy in the latter population.

Purpose

We sought to compare the diagnostic test accuracy of DSC and arterial spin-labeling (ASL), in their ability to differentiate between low- and high-grade pediatric brain tumors at first presentation.

Data sources

Articles were retrieved from online electronic databases: MEDLINE (Ovid), Web of Science Core Collection, and Scopus.

Study selection

Stu

SUBMITTER: Vella S 

PROVIDER: S-EPMC11735421 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature