Inter- and Intrarater Agreement of CT Brain Calcification Scoring in Primary Familial Brain Calcification.

ABSTRACT:

Background and purpose

The total calcification score (TCS) is a visual rating scale to measure primary familial brain calcification (PFBC)-related calcification severity on CT. We investigated the inter- and intrarater agreement of a modified TCS.

Materials and methods

Patients aged ≥18 years with PFBC or Fahr syndrome who visited the outpatient clinic of a Dutch academic hospital were included. The TCS was modified, for example, by adding hippocampal calcification, and ranged from 0 to 95 points. Fifteen raters evaluated all CTs, of whom 3 evaluated the CTs twice. Their entrustable professional activity (EPA) level ranged from II (medical student) to V (neuroradiologist). Agreement was assessed by using the intraclass correlation coefficient (ICC) for the total score. Kenda

SUBMITTER: Snijders BMG 

PROVIDER: S-EPMC11735432 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature