Systematic qualitative proteome-wide analysis of lysine malonylation profiling in Platycodon grandiflorus.

ABSTRACT: In recent years, it was found that lysine malonylation modification can affect biological metabolism and play an important role in plant life activities. Platycodon grandiflorus, an economic crop and medicinal plant, had no reports on malonylation in the related literature. This study qualitatively introduces lysine malonylation in P. grandiflorus. A total of 888 lysine malonylation-modified proteins in P. grandiflorus were identified, with a total of 1755 modification sites. According to the functional annotation, malonylated proteins were closely related to catalysis, binding, and other reactions. Subcellular localization showed that related proteins were enriched in chloroplasts, cytoplasm, and nuclei, indicating that this modification could regulate various metabolic processes. Motif a

SUBMITTER: Yang Q 

PROVIDER: S-EPMC11735498 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature