Impact of ⁶⁸Ga-FAPI positron emission tomography/computed tomography on staging and tumor management in patients with gastric cancer.

ABSTRACT:

Purpose

To evaluate the added value of additional ⁶⁸Ga-FAPI PET/CT following CT for primary staging, detection of postoperative recurrence, and management of gastric cancer patients.

Methods

We retrospectively included patients with gastric cancers who underwent contrast-enhanced computed tomography (ceCT), followed by ⁶⁸Ga-FAPI PET/CT within 30 days. ⁶⁸Ga-FAPI PET/CT was performed for initial staging or detection of postoperative recurrence. Two nuclear medicine physicians and a radiologist independently decided on imaging-based staging. Pre-⁶⁸Ga-FAPI PET/CT treatment decisions were made by a simulated tumor board and post-⁶⁸Ga-FAPI PET/CT decisions were extracted from medical records. We evaluated the impact of ⁶⁸

SUBMITTER: Zhang S 

PROVIDER: S-EPMC11735559 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature