Excitatory-inhibitory homeostasis and bifurcation control in the Wilson-Cowan model of cortical dynamics.

ABSTRACT: Although the primary function of excitatory-inhibitory (E-I) homeostasis is the maintenance of mean firing rates, the conjugation of multiple homeostatic mechanisms is thought to be pivotal to ensuring edge-of-bifurcation dynamics in cortical circuits. However, computational studies on E-I homeostasis have focused solely on the plasticity of inhibition, neglecting the impact of different modes of E-I homeostasis on cortical dynamics. Therefore, we investigate how the diverse mechanisms of E-I homeostasis employed by cortical networks shape oscillations and edge-of-bifurcation dynamics. Using the Wilson-Cowan model, we explore how distinct modes of E-I homeostasis maintain stable firing rates in models with varying levels of input and how it affects circuit dynamics. Our results confirm tha

SUBMITTER: Pascoa Dos Santos F 

PROVIDER: S-EPMC11737862 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature