Dynamics of Persistent Submicroscopic and Microscopic Plasmodium falciparum in Pregnant Women Under Intermittent Preventive Treatment: A Study Cohort in Benin.

ABSTRACT:

Background

Malaria infections in pregnancy are a major cause of maternal morbidity and neonatal mortality in sub-Saharan Africa. A high proportion of these infections are submicroscopic, which are usually asymptomatic and therefore untreated during pregnancy. Intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) aims to prevent and treat all potential infections whether submicroscopic or not. However, the resistance of parasites to SP is steadily increasing. The dynamic of microscopic and submicroscopic infections in a cohort of Beninese women throughout their pregnancy and its relation to IPTp-SP has been assessed.

Methods

As a subsample of the RECIPAL project, 130 women with at least 2 infections detected by polymerase chain reaction during their pregn

SUBMITTER: Jafari-Guemouri S 

PROVIDER: S-EPMC11739809 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature