Current landscape of immunotherapy in esophageal cancer: a literature review.

ABSTRACT:

Background and objective

Esophageal cancer has witnessed a significant shift in its epidemiology within the United States. Adenocarcinoma of the esophagus is now the fastest-growing solid malignancy, surpassing esophageal squamous cell carcinoma (ESCC) in frequency. There has been a concentrated effort to establish new therapies for dealing with this malignancy including immunotherapy in conjunction with surgery and radiotherapy. Our objective is to provide a comprehensive review of the current therapeutic strategies for esophageal cancer, with a particular focus on the emerging role of immunotherapy in combination with surgery and radiotherapy, and its impact on treatment outcomes.

Methods

A thorough search was done using keywords of "esophageal cancer", "immunotherapy in e

SUBMITTER: Moughnyeh MM 

PROVIDER: S-EPMC11740023 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature