Association of Seizure Control with Mortality, Cognition, and Function in People With Dementia.

ABSTRACT:

Objectives

The effects of seizure control on outcomes in persons with dementia (PWD) remain unclear. Our study aimed to investigate the impact of seizure control on mortality, function, cognition, and mood among PWD.

Methods

This longitudinal, multicenter study is based on 39 Alzheimer's disease centers (ADCs) in the United States from September 2005 to December 2021. PWD were grouped by seizure status into recurrent (seizures in the past year), remote (prior seizures but none in the past year), and no seizures (controls). The primary outcome was all-cause mortality among seizure groups. We used Weibull survival analysis to assess the mortality risks by seizure status after adjusting for age, sex, education, race, ethnicity, hypertension, diabetes, hyperlipidemia, degree of

SUBMITTER: Zawar I 

PROVIDER: S-EPMC11740283 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature