Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury.

ABSTRACT:

Background

Emerging evidence suggests that there are morphological and physiological changes to the vastus lateralis after an anterior cruciate ligament (ACL) tear. However, it is unclear whether these alterations are limited to just the vastus lateralis or are more representative of widespread changes across the thigh musculature and/or if these changes precede reconstruction. The purpose of this study was to determine T1ρ relaxation time, a measure of extracellular matrix organization in muscle, and physiological cross-sectional area (PCSA) for muscles of the quadriceps and hamstrings of the ACL-deficient and contralateral limbs soon after ACL injury.

Methods

T1ρ and diffusion tensor magnetic resonance imaging were performed on both limbs of 10 participants after primary A

SUBMITTER: Owen MK 

PROVIDER: S-EPMC11740430 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature