High-Sensitivity Detection of Chiro-Optical Effects in Single Nanoparticles by Four-Wave Mixing Interferometry.

ABSTRACT: The field of chiral nanoparticles is rapidly expanding, yet measuring the chirality of single nano-objects remains a challenging endeavor. Here, we report a technique to detect chiro-optical effects in single plasmonic nanoparticles by means of phase-sensitive polarization-resolved four-wave mixing interferometric microscopy. Beyond conventional circular dichroism, the method is sensitive to the particle polarizability, in amplitude and phase. First, we demonstrate its application on single chiral nanohelices fabricated by focused ion beam induced deposition. We examined the combination of detected fields, which measures the particle polarizability, and showed that this is a sensitive reporter of chirality, providing dissymmetry factors (g _α) impressively approaching unit

SUBMITTER: Borri P 

PROVIDER: S-EPMC11741159 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature