Associations between social behaviour and proinflammatory immune activation are modulated by age in a free-ranging primate population.

ABSTRACT: The effect of the social environment on the proinflammatory immune response may mediate the relationship between social environment and fitness but remains understudied outside captive animals and human populations. Age can also influence both immune function and social behaviour, and hence may modulate their relationships. This study investigates the role of social interactions in driving the concentrations of two urinary markers of proinflammatory immune activation, neopterin and soluble urokinase plasminogen activator receptor (suPAR), in a free-ranging population of rhesus macaques, Macaca mulatta. We collected 854 urine samples from 172 adult monkeys and quantified how urinary suPAR and neopterin concentrations were related to affiliative behaviour and agonistic behaviour recei

SUBMITTER: Cooper EB 

PROVIDER: S-EPMC11741183 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature