Early clinical predictors of infected pancreatic necrosis: a multicentre cohort study.

ABSTRACT:

Background

Infected pancreatic necrosis (IPN) exacerbates complications in patients with acute pancreatitis (AP), increasing mortality rates if not treated promptly. We aimed to evaluate the predictive value of clinical characteristics within 24 hours of admission for IPN prediction.

Methods

We conducted a retrospective, multicentre cohort study including 3005 patients with AP from eight hospitals in China. Clinical variables collected within 24 hours after admission were analysed using least absolute shrinkage and selection operator regression (10 cross-validations) for variable selection, followed by multivariate logistic regression to develop an IPN prediction model. Internal cross-validation of the development set and validation of the validation set were performed to en

SUBMITTER: Song K 

PROVIDER: S-EPMC11741192 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature