Hierarchical substrates of prediction in visual cortical spiking.

ABSTRACT: Predictive processing models have recently flourished in neuroscience ^1-9 . Feedforward and feedback modulation are at the heart of these hierarchical predictive processing models. Previous experimental studies using fMRI, EEG/MEG, and LFP ^1,10,11 could not reliably resolve feedback modulation from local computations and feedforward outputs. Here, using open-science ⁹ , multi-species, multi-area, high-density ¹² , laminar neurophysiology ¹³ , we empirically test whether predictive processing is a key component shaping sensation. To isolate sensory information processing and eliminate motor/reward confounders ^1,10,11 , we use a no-report task. Our task leveraged so-called global oddballs (GO) as unpredictable, deviant stimuli

SUBMITTER: Westerberg JA 

PROVIDER: S-EPMC11741236 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature