CHOLINERGIC MODULATION OF CELLULAR RESONANCE IN NON-HUMAN PRIMATE HIPPOCAMPUS.

ABSTRACT: Acetylcholine modulates the network physiology of the hippocampus, a crucial brain structure that supports cognition and memory formation in mammals ^1-3. In this and adjacent regions, synchronized neuronal activity within theta-band oscillations (4-10Hz) is correlated with attentive processing that leads to successful memory encoding ^4-10. Acetylcholine facilitates the hippocampus entering a theta oscillatory regime and modulates the temporal organization of activity within theta oscillations ^11,12. Unlike rodents that exhibit constant theta oscillations during movement and exploration, primates only manifest theta oscillations in transient bouts during periods of acute attention-despite conserved hippocampal anatomy ^13-16. The phasic nature of p

SUBMITTER: Gambrill A 

PROVIDER: S-EPMC11741476 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature