Optimization of HIV drugs through MCDM technique Analytic Hierarchy Process(AHP).

ABSTRACT: Topological indices are crucial tools for predicting the physicochemical and biological features of different drugs. They are numerical values obtained from the structure of chemical molecules. These indices, particularly the degree-based TIs are a useful tools for evaluating the connection between a compound's structure and its attributes. This study addresses the research problemof how to optimize drug design for HIV treatment using degree-based topological indices. The need for safer and more effective medicines for HIV is further emphasized by the advent of drug resistance and severe negative effects from current therapies. Employing degree-based graph invariants, the study investigates 13 HIV drugs by applying a quantitative structure-property relationship (QSPR) technique to associat

SUBMITTER: Farooq FB 

PROVIDER: S-EPMC11741607 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature