Decavanadate Compound Displays In Vitro and In Vivo Antitumor Effect on Melanoma Models.

ABSTRACT: The efficacy of available treatments for melanoma is limited by side effects and the rapidly emerging resistance to treatment. In this context, the decavanadate compounds represent promising tools to design efficient therapeutic agents. In our study, we synthesized a dimagnesium disodium decavanadate icosahydrate compound (Mg₂Na₂V₁₀O₂₈·20H₂O) and investigated its structure stability as well as its antimelanoma effects. Results showed that the Mg₂Na₂V₁₀O₂₈·20H₂O compound is structured in a monoclinic system with the space group C2/c, stabilized by oxygen vertices, hydrogen bonds, and van der Waals interactions. Interestingly, we found that this newly synthesized compound reduced the

SUBMITTER: Essid A 

PROVIDER: S-EPMC11742080 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature