Cola beverage reduces risk of lead poisoning from accidental ingestion of contaminated soil particles in rat and swine models.

ABSTRACT: Accidental ingestion of lead (Pb)-contaminated soils represents a major route of Pb exposure for both adults and children, and the development of accessible and cost-effective solutions to reduce Pb poisoning is urgently required. Here, we present an effective and straightforward technique, involving the consumption of cola beverages, for the purpose of lowering blood Pb levels following the ingestion of contaminated soils in animal models. This method facilitated the direct passage of Pb in contaminated soil through the digestive system, enhancing its elimination without absorption into systemic circulation. Our results demonstrated that cola effectively reduced Pb bioaccessibility in 22 contaminated soils by 32.6%-98.8%. In male rats and swine exposed to Pb-contaminated soils, cola treat

SUBMITTER: Xu X 

PROVIDER: S-EPMC11742081 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature