QuICSeedR: an R package for analyzing fluorophore-assisted seed amplification assay data.

ABSTRACT:

Motivation

Fluorophore-assisted seed amplification assays (F-SAAs), such as real-time quaking-induced conversion (RT-QuIC) and fluorophore-assisted protein misfolding cyclic amplification (F-PMCA), have become indispensable tools for studying protein misfolding in neurodegenerative diseases. However, analyzing data generated by these techniques often requires complex and time-consuming manual processes. In addition, the lack of standardization in F-SAA data analysis presents a significant challenge to the interpretation and reproducibility of F-SAA results across different laboratories and studies. There is a need for automated, standardized analysis tools that can efficiently process F-SAA data while ensuring consistency and reliability across different research settings.

Resul

SUBMITTER: Li M 

PROVIDER: S-EPMC11742141 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature