Persistent NK cell deficiency associated with pulmonary cryptococcosis.

ABSTRACT: We describe pulmonary cryptococcosis in a 28-year-old previously healthy man. Exhaustive immunological investigations revealed a primary NK cell deficiency associated with a secondary impaired anti-Cryptococcus CD8 lymphocyte response and the expansion of a CD8Vβ14 + T cell clone. This case illustrates the potential role of NK cells in immunity against Cryptococcus.

SUBMITTER: Martinot M 

PROVIDER: S-EPMC11742195 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature