The GeoTox Package: open-source software for connecting spatiotemporal exposure to individual and population-level risk.

ABSTRACT:

Background

Comprehensive environmental risk characterization, encompassing physical, chemical, social, ecological, and lifestyle stressors, necessitates innovative approaches to handle the escalating complexity. This is especially true when considering individual and population-level diversity, where the myriad combinations of real-world exposures magnify the combinatoric challenges. The GeoTox framework offers a tractable solution by integrating geospatial exposure data from source-to-outcome in a series of modular, interconnected steps.

Results

Here, we introduce the GeoTox open-source R software package for characterizing the risk of perturbing molecular targets involved in adverse human health outcomes based on exposure to spatially-referenced stressor mixtures. We demon

SUBMITTER: Messier KP 

PROVIDER: S-EPMC11742212 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature