Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA).

ABSTRACT: Standard information reporting helps to ensure that assay conditions and data are consistently reported and to facilitate inter-laboratory comparisons. Here, we present recommendations on minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA). The TEER assay is extensively used to evaluate the health of an epithelial/endothelial cell culture model and as an indicator of the potential toxicity of a test substance. This publication is the result of an international collaboration─called the RespTox (Respiratory Toxicity) Collaborative─through which twelve laboratories shared their protocols for assessing the barrier function of respiratory epithelial cells using the TEER assay following exposure to substances. The protocols from each l

SUBMITTER: Sharma M 

PROVIDER: S-EPMC11742365 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature