C-Phycocyanin and Phycocyanobilin as a Novel Adjuvant in Hepatitis B Vaccine.

ABSTRACT:

Background

Vaccine adjuvants are components that enhance immune responses to an antigen. Given the importance of adjuvants, research on novel adjuvants with higher efficacy and fewer adverse effects remains crucial. Spirulina (Arthrospira sp.), an aqueous, photosynthetic, filamentous, spiral, multicellular microalga also classified as a cyanobacterium, is well known for its high protein content, vitamins, essential fatty acids, and amino acids. C-phycocyanin (C-PC) is one of the most significant proteins in Spirulina.

Objectives

This study aimed to investigate the adjuvant capabilities of three Spirulina-derived substances-Spirulina extract, C-phycocyanin (C-PC), and phycocyanobilin (PCB)-in conjunction with the Hepatitis B surface antigen

SUBMITTER: Abdali N 

PROVIDER: S-EPMC11742379 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature