Comparison of 1D and 3D volume measurement techniques in NF2-associated vestibular schwannoma monitoring.

ABSTRACT: To compare 1D (linear) tumor volume calculations and classification systems with 3D-segmented volumetric analysis (SVA), focusing specifically on their effectiveness in the evaluation and management of NF2-associated vestibular schwannomas (VS). VS were clinically followed every 6 months with cranial, thin-sliced (< 3 mm) MRI. We retrospectively reviewed and used T1-weighted post-contrast enhanced (gadolinium) images for both SVA and linear measurements. 3D-SVA was performed manually or combined with semiautomated segmentation by using axial planes. The maximum linear dimensions (MLD) were determined in three dimensions (anteroposterior, transverse, and craniocaudal planes) using axial and coronal planes. The MLD was cubed (MLD³), and orthogonal analysis (OA) was derived to esta

SUBMITTER: Gugel I 

PROVIDER: S-EPMC11742393 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature