Long-term characterization of behavior phenotypes in children with seizures: Analytic approach matters.

ABSTRACT:

Objective

Behavioral problems in children with new onset epilepsies have been well established in the literature. More recently, the literature indicates the presence of unique behavioral patterns or phenotypes in youth with epilepsy that vary significantly in vulnerability and resilience to behavioral problems. This study contrasts the interpretation of behavioral risk as inferred from cross-sectional versus latent group analytic perspectives, as well as the presence, consistency, stability, and progression of behavioral phenotypes in youth with new onset epilepsy and sibling controls over 3 years.

Methods

Three hundred twelve participants (6-16 years old) were recruited within 6 weeks of their first recognized seizure along with 223 unaffected siblings. Each child's behavi

SUBMITTER: Morales K 

PROVIDER: S-EPMC11742550 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature