Prediction of cardiac remodeling and myocardial fibrosis in athletes based on IVIM-DWI images.

ABSTRACT: Myocardial microcirculation in athletes and its relationship with cardiac remodeling (CR) and myocardial fibrosis (MF) are not fully understood. We prospectively enrolled 174 athletes and 54 healthy sedentary controls for intravoxel incoherent motion (IVIM) diffusion-weighted imaging of cardiac magnetic resonance imaging. Athletes exhibited significantly lower fast apparent diffusion coefficient (ADC_fast) and perfusion fraction (f) in 16 myocardial segments and each blood supply area compared to controls (p < 0.05). Athletes with CR and/or MF had lower myocardial slow apparent diffusion coefficient (ADC_slow) values than those without (p < 0.05). A gradient boosting machine (GBM) effectively predicted CR and/or MF based on these hypoperfusion parameters,

SUBMITTER: Deng Y 

PROVIDER: S-EPMC11742616 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature