The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired pneumonia patients with type 2 diabetes mellitus.

ABSTRACT:

Background

The features of community-acquired pneumonia (CAP) patients with type 2 diabetes mellitus (T2DM) differ from those without. This study aims to spot a routinely tested parameter with discriminative, predictive and prognostic value to enhance CURB-65's prognostic accuracy in CAP patients with T2DM.

Methods

We retrospectively studied consecutive CAP patients from 2020 to 2021, comparing laboratory parameters between patients with and without T2DM. Receiver operating characteristic (ROC) curve analysis, univariate and multivariate logistic regression were used to identify key parameters. The area under the ROC curve (AUC), Fagan's nomogram, net reclassification improvement (NRI), and integrated discrimination improvement (IDI) evaluated the added predictive accuracy.<

SUBMITTER: Zhou H 

PROVIDER: S-EPMC11742778 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature