Nasal microbial diversity is associated with survival in piglets infected by a highly virulent PRRSV-1 strain.

ABSTRACT:

Background

Porcine reproductive and respiratory syndrome virus (PRRSV) is a major threat to swine industry worldwide, especially virulent variants arising during the last years, such as Spanish PRRSV-1 Rosalia strain. The role of the nasal microbiota in respiratory viral infections is still to be unveiled but may be promisingly related with the health status of the animals and thus, their susceptibility. The goal of this project was to study the nasal microbiota composition of piglets during a highly virulent PRRSV-1 outbreak comparing animals that died due to the infection with animals that survived it. The microbiota composition was inferred by V3-V4 regions of the 16S rRNA gene sequencing and bioinformatics analysis. To deepen the analysis, we added samples taken from piglets be

SUBMITTER: Obregon-Gutierrez P 

PROVIDER: S-EPMC11742779 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature