Comparison of stimulation sites enhancing dual-task performance using transcranial direct current stimulation in Parkinson's disease.

ABSTRACT: This pilot randomized crossover study aimed to compare the effects of stimulating various transcranial direct current stimulation (tDCS) target sites to improve dual-task performance in patients with Parkinson's disease (PD). Nineteen patients with idiopathic PD completed four sessions of 2 mA anodal tDCS for 20 min at randomly assigned sites: the primary motor cortex (M1), left dorsolateral prefrontal cortex (DLPFC), ventromedial prefrontal cortex, and sham stimulation. Anodal M1 tDCS induced statistically significant improvements in single-task and cognitive dual-task timed up and go test. Additionally, enhancements were noted in the color-word Stroop test and trail-making test-Trail B following left DLPFC stimulation. However, none of the stimulation sites showed any significant changes

SUBMITTER: Yun SJ 

PROVIDER: S-EPMC11742881 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature