High prevalence of fecal carriage of extended-spectrum beta-lactamase producing <i>Enterobacterales</i> among patients with urinary tract infections in rural Tanzania.

ABSTRACT:

Introduction

The global rise of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) challenges resource-limited countries with insufficient laboratory infrastructure. This study investigates fecal carriage and risk factors for ESBL-PE and carbapenemase-producing organisms among patients with urinary tract infection (UTI) in rural Tanzania.

Methods

This cross-sectional study was conducted at St. Francis Regional Referral Hospital, Ifakara, Tanzania, from October 2021 to August 2023, involving 326 UTI patients. Demographic data and resistance risk factors were collected via structured questionnaires. Stool samples collected pre-antibiotic treatment were screened for ESBL-PE and carbapenemase locally. Positive samples underwent further analysis in Switz

SUBMITTER: Macha ME 

PROVIDER: S-EPMC11743186 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature