Association between penicillin allergy labels and serious adverse events in hospitalized patients: a systematic review and meta-analysis.

ABSTRACT:

Background

To date, several studies have demonstrated that erroneous labeling of Penicillin allergy (PAL) can significantly impact treatment options and result in adverse clinical outcomes, while other studies have reported no negative effects. Therefore, to systematically evaluate these effects and investigate the association between adverse clinical outcomes and the Penicillin label, we conducted this meta-analysis.

Method

Searches were conducted in the PubMed, Embase, Cochrane Library, and Web of Science databases from inception to 13 July 2024. The search strategy utilized terms ("antibiotic allergy label," "penicillin allergy label," and "allergy label") and ("death," "readmission," "adverse outcome," and "clinical adverse outcome"). In the study selection process, the

SUBMITTER: Zhang S 

PROVIDER: S-EPMC11743256 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature