Healthcare resource utilisation and direct medical cost for individuals with 5q spinal muscular atrophy in Sweden.

ABSTRACT:

Background

Spinal muscular atrophy (SMA) is a rare, progressive, neuromuscular disorder. Recent advances in treatment require an updated assessment of burden to inform reimbursement decisions.

Objectives

To quantify healthcare resource utilisation (HCRU) and cost of care for patients with SMA.

Methods

Cohort study of patients with SMA identified in the Swedish National Patient Registry (2007-2018), matched to a reference cohort grouped into four SMA types (1, 2, 3, unspecified adult onset [UAO]). HCRU included inpatient admissions, outpatient visits, procedures, and dispensed medications. Direct medical costs were estimated by multiplying HCRU by respective unit costs. Average annual HCRU and medical costs were modelled for SMA versus reference cohorts to estimate dif

SUBMITTER: Sejersen T 

PROVIDER: S-EPMC11743398 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature