Comparative efficacy of neuroprotective agents for improving neurological function and prognosis in acute ischemic stroke: a network meta-analysis.

ABSTRACT:

Background

Ischemic stroke is the second leading cause of death and the third leading cause of combined disability and mortality globally. While reperfusion therapies play a critical role in the management of acute ischemic stroke (AIS), their applicability is limited, leaving many patients with significant neurological deficits and poor prognoses. Neuroprotective agents have garnered attention for their potential as adjunct therapies; however, their relative efficacy remains unclear. This study utilized a network meta-analysis (NMA) to systematically compare the efficacy of neuroprotective agents in improving neurological function and prognosis in stroke patients.

Methods

This study adhered to PRISMA guidelines and the Cochrane Handbook for systematic reviews. Randomized co

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11743486 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature