Microstructure of the human metastatic vertebral body.

ABSTRACT:

Introduction

Bone spinal metastases disrupt the bone homeostasis, inducing a local imbalance in the bone formation and/or resorption, with consequent loss of the structural optimisation of the vertebrae and increase of the risk of fracture. Little is known about the microstructure of the metastatic tissue, the microstructure of the tissue surrounding the lesion, and how it does compare with vertebrae with no lesions observed on the biomedical images. A comprehensive assessment of the microstructural properties of the entire vertebral body can be obtained with micro computed tomography. In this study, we evaluated to what extent the vertebral body is affected by the presence of a metastatic lesion, the properties of the metastatic lesions, and whether the tissue surrounding the lesi

SUBMITTER: Cavazzoni G 

PROVIDER: S-EPMC11743553 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature