Lower limb lymphoedema-related mental depression: A systematic review and meta-analysis of non-cancer-related studies.

ABSTRACT:

Background

Lower limb lymphoedema, characterized by persistent swelling in the legs due to lymphatic dysfunction, not only imposes a physical burden but is also associated with significant mental depression. While emerging research suggests a strong link between lower limb lymphoedema and depression, the extent of the problem remains underexplored. This study aims to investigate the relationship between lower limb lymphoedema and mental depression through a meta-analysis of existing studies.

Methods

A comprehensive search was conducted across databases including PubMed, MEDLINE, EMBASE, International Scientific Indexing, Web of Science, and Google Scholar. Study quality was assessed using the Joanna Briggs Institute (JBI) critical appraisal tool. A weighted inverse variance

SUBMITTER: Kitaw TA 

PROVIDER: S-EPMC11743871 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature