Connectional differences between humans and macaques in the MT+ complex.

ABSTRACT: MT+ is pivotal in the dorsal visual stream, encoding tool-use characteristics such as motion speed and direction. Despite its conservation between humans and monkeys, differences in MT+ spatial location and organization may lead to divergent, yet unexplored, connectivity patterns and functional characteristics. Using diffusion tensor imaging, we examined the structural connectivity of MT+ subregions in macaques and humans. We also employed graph-theoretical analyses on the constructed homologous tool-use network to assess their functional roles. Our results revealed location-dependent connectivity in macaques, with MST, MT, and FST predominantly connected to dorsal, middle, and ventral surfaces, respectively. Humans showed similar connectivity across all subregions. Differences in connecti

SUBMITTER: Ruan J 

PROVIDER: S-EPMC11743884 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature