Dual-layer detector spectral computed tomography quantitative parameters for predicting pathological complete remission after neoadjuvant treatment of breast cancer.

ABSTRACT:

Background

Breast cancer (BC) is a common cancer among women worldwide, and although the use of neoadjuvant therapy (NAT) for BC has become more widespread, there is no standardized prediction of the efficacy of NAT for BC. This study aimed to evaluate the value of quantitative parameters of dual-layer detector spectral computed tomography (DLCT) in predicting whether BC patients can achieve pathological complete response (pCR) after NAT.

Methods

Patients who were first diagnosed with BC in Shandong Cancer Hospital and Institute and received only NAT before surgery were selected for participation in this study. All breast computed tomography (CT) imaging examinations were performed using DLCT, within 1 week before initiating NAT. The gold standard for evaluating the effect o

SUBMITTER: Guo S 

PROVIDER: S-EPMC11744159 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature