Photo- and Cobalt-Catalyzed Cycloisomerization of Unsaturated Guanidines, (Iso-)Ureas, and Carbonates.

ABSTRACT: We report intramolecular photocatalyzed cycloisomerization of unactivated olefins with pendant nucleophiles. The reaction proceeds under mild conditions and utilizes guanidines, ureas, isoureas, isothioureas, and carbonates to yield several different five-, six-, and seven-membered heterocycles. Use of benzothiazinoquinoxaline as an organophotocatalyst and cobalt-salen catalyst obviates the need for a stoichiometric oxidant or reductant.

SUBMITTER: Lindner H 

PROVIDER: S-EPMC11744792 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature