External validation of a novel cancer-associated venous thromboembolism risk assessment score in a safety-net hospital.

ABSTRACT:

Background

Cancer-associated thrombosis (CAT) is a leading cause of death in patients diagnosed with cancer. However, pharmacologic thromboprophylaxis use in cancer patients must be carefully evaluated due to a 2-fold increased risk of experiencing a major bleeding event within this population. The electronic health record CAT (EHR-CAT) risk assessment model (RAM) was recently developed, and reports improved performance over the widely used Khorana score. Extensive RAM external validation is crucial to determine accuracy across diverse patient populations prior to clinical utilization.

Objectives

To externally validate EHR-CAT using data from 2103 patients with cancer at the Boston Medical Center (BMC), New England's largest safety-net hospital, and to compare this RAM with

SUBMITTER: Dulberger KN 

PROVIDER: S-EPMC11745955 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature