Prognostic value of the pretreatment Naples prognostic score in patients with colorectal cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

The prognostic significance of the Naples prognostic score (NPS) in colorectal cancer remains uncertain. This study aims to investigate the correlation between the pretreatment NPS and long-term oncological outcomes in patients with colorectal cancer.

Methods

A comprehensive literature search of electronic databases, including PubMed, Embase, and Web of Science, was conducted up to July 1^st, 2024. The primary outcomes assessed were survival outcomes. Subgroup analysis and sensitivity analysis were performed during the pooled analysis.

Results

Eight studies including 2571 patients were included. The pooled results indicated that patients in the high NPS group exhibited significantly worse overall survival (HR= 2.08 95%CI: 1.74-2.48; P<0.01; I

SUBMITTER: Liu H 

PROVIDER: S-EPMC11746047 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature